Archive for the ‘Naproxen Sodium’ category

The differences between Naproxen Sodium vs Ibuprofen

January 24th, 2014

Most people believe that there is no difference between naproxen sodium vs. ibuprofen or any other pain reliever. However, this happens because when they feel pain they go and pick any pain reliever bottle around.  Moreover, there is different medication for different ailments and the side effects also different immensely. If you plan taking a regular dose, it is important to consider consulting the physician for the side effects and the efficacy of the drug. Naproxen sodium vs ibuprofen differs mainly due to the fact that they do not treat the same conditions and the dosage recommendation is different. The adverse effects caused by the use of the medications can be also a clear difference. Although they may be similar in that they are non-steroidal anti-inflammatory drugs or NSAIDs as they are popularly known the two have peculiar differences. The two drugs share some treatment indications and side effects as well. Reviewing the similarities between naproxen sodium vs ibuprofen can help you understand the differences properly.  Both reduce inflammation, they are NSAIDs, diminish fever and relieve pain. The bioavailability of each of the medicine is similar and they can be purchased at a local drug store or prescribed by a doctor. The mechanism of action between naproxen sodium vs ibuprofen is similar as they act in inhibiting the enzyme referred to as cyclooxygenase or COX. In specific pharmacology, the two drugs inhibit the production of COX2 and COX1, which in turn reduce or lowers the body’s production of prostaglandins.children-148898_640
Either of the drugs is useful in treating certain conditions such as general pain or menstrual cramping per se. The side effects tend to be similar although some may differ, some of these include stomach upset, nausea, vomiting, and the likelihood of gastric ulcer development. The major difference between naproxen sodium vs ibuprofen is the dosage of the medication.  For the over, the counter medications of sodium naproxen people often use 200-250 milligrams after eight hours and an adult dosage of ibuprofen is 400 milligrams for 4-6 hours. However the dosage can differ depending on the condition being treated, patients often take less of the naproxen due to its efficacy and the strength in milligram for milligram than ibuprofen. Despite the fact that the two medicines can share some of the recommendations, there are other medical conditions that are better when one of them is used to treat it. Naproxen is recommend for people with any form of gout, bursitis, tendonitis and arthritis on the other and ibuprofen is suitable for headache, fever, toothache and other,musculoskeletal injuries. The drugs have a difference in their side effects, both shares the risk of developing of gastric ulcers although the level of risk in each varies greatly. Naproxen has the potential to generate such kind of side effect and may increase the risk of getting birth defects. On the other hand, ibuprofen has a higher chance of contributing to stomach pains and headaches.
In Ibuprofen vs. Naproxen, the major difference is the speed of action; ibuprofen is faster than naproxen sodium. Ibuprofen is known to bring fast and quicker relief to pain than the naproxen sodium. Regardless of the fact that ibuprofen can cause quick pain relief, it may adverse side effects on the heart and the liver of the patient due to the toxins generated during its degradation. Naproxen on the other hand may take a long time in creating relief from the pain however; it provides a long-term solution to the problem. It has a better effect when targeting muscular inflammations, and pains that could be caused by strained or sprained muscles or arthritis. Despite the fact that no medication is a cure all naproxen sodium and ibuprofen are the two widely used drugs and they have a low rate of direct causes of hospitalization or death. Some studies have indicated that naproxen carries some risks of heart attack and for people with heartburn or high blood pressure should consult a physician before buying the medication. The similarities between naproxen sodium vs ibuprofen can make the selection of pain relieving drugs difficult; however as a patient weighing the advantages and disadvantages of both drugs and choose whichever suits them. For people who want to use the drug on a regular basis, then consultation with a medical practitioner deems necessary.
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Naproxen Sodium – Take as per the prescription!

March 27th, 2012

There are a few things that you should take into consideration while consuming naproxen sodium. It’s often advisable for you to take this medicine along with a glass of water and food so that stomach upset like effects can be avoided successfully. At the same time you even need to take the naproxen sodium as per the prescribed dosage from the doctor. It’s always better to maintain a gap of at least eight hours among these dosages. Intake of naproxen sodium can even generate few side effects but they are always mild and will go soon. However, there are only few cases registered when people have come across side effects related to naproxen sodium. It’s a popular medication and can be used to treat body pain generated due to arthritis. It can also treat menstrual cramps elegantly.  Naproxen sodium is also in use to treat intestinal holes and stomach ulcers.

Some other serious side effects also include shortness of the breath, chest pain, persistent stomach pain, slurred speech, coffee grounds-such as vomit, black stools, as well as weakness on either side of body. Drug might cause you blood clots, which can result in the heart attack and stroke. These things are serious however rare while taking the naproxen sodium. Rarely, drug is known to cause the possibly fatal disease. The signs of the liver disease include extreme tiredness, dark urine, vomiting or persistent nausea, severe abdominal pain, as well as yellowing of eyes and skin. Naproxen is effective nonselective inhibitor of the cyclo-oxygenase, resulting in inhibition of the prostaglandin synthesis mediated through COX-1 & COX-2. Naproxen sodium improved solubility of the naproxen, attaining fast absorption as well as fast onset of the action.

Though evidence from the clinical studies suggests naproxen sodium gives you better headache relief than the placebo in treatment of the migraine headache, it is not known if it gives you any clinical benefits that are taken in account desired outcomes in the acute migraine therapy like recommended by International Headache Society. To best of knowledge, there is not any previously published review as well as meta analysis of the naproxen sodium for the acute migraine attacks. Thus, we undertook the meta analysis to evaluate efficacy of the naproxen sodium in attempt to decide the therapeutic benefit in treatment of the acute migraine attacks.


Naproxen While Breastfeeding

January 17th, 2012

Naproxen is found in breast milk. It is not recommended to breast- feed while taking Naproxen. Additionally, Naproxen could cause harm to the unborn child. Don’t take it during the last three months of being pregnant. If you feel you might be pregnant, consult your physician. You will have to talk about the advantages and dangers of taking Naproxen Sustained- Release Tablets while you’re pregnant. Naproxen Sustained- Release Tablets shouldn’t be used while in labor.

Reason why Naproxen is prescribed by doctors

Naproxen is a non-steroidal anti- inflammatory medication helpful to relieve menstrual cramps and mild to moderate pain. Naproxen can also be recommended for relief of the inflammation, stiffness, swelling, and joint pain related to rheumatoid arthritis and osteoarthritis, as well as for spinal arthritis, tendonitis, acute gout, bursitis,  along with other disorders. Naproxen may also be advised for juvenile arthritis.

Naproxen side effects

If you take naproxen on a regular basis you can develop internal bleeding and ulcers. One more Naproxen side effect is harm to kidneys. A long term naproxen unwanted effect might be hearing problems. Naproxen side effects might not be anticipated. If any naproxen unwanted effects develop or alter in intensity, tell your physician at the earliest opportunity.
Other side negative effects of Naproxen can include: headache, bruising, indigestion, diarrhea, difficult or labored breathing, abdominal pain , dizziness, drowsiness, rapid, fluttery heartbeat, hearing disturbances, constipation, heartburn, inflammation of the mouth, itching, light -headedness, nausea,  vertigo, red or purple spots on the skin, ringing in the ears, swelling due to fluid retention, skin eruptions, sweating, thirst, vision changes.

Use during lactation

Minimal info suggests that amounts of naproxen in breast milk are low and uncomfortable side effects in breastfed babies are evidently unusual. Nevertheless, due to naproxen’s long half- life and noted serious adverse reaction in a breastfed neonate, other agents might be favored while nursing an infant or preterm infant.

Drug Levels

Maternal Levels: Peak milk naproxen levels in a five month postpartum patient were 1.1 to 1.3 mg /L while taking oral naproxen 250 mg two times a day and two, 4 mg/L with a dosage of 375 mg two times a day. Peak milk amounts took place4 to 5 hrs after the dose and fell gradually over twelve to twenty four hours. From urinary excretion data the observers projected that the infant received. Twenty six percent of the mother’s whole doses or 1.9% of the maternal weight- adjusted dosage. Using the peak milk level data, the projected highest consumption of an exclusively breastfed infant will be 2.

Effects in Breastfed Infants

Naproxen perhaps triggered extended bleeding time, acute anemia and thrombocytopenia in one 7-day old infant in a mother also taking bacampicillin. In one study of twenty infants exposed to Naproxen during breastfeeding, two mothers reported drowsiness and one reported vomiting in their infants.  None of the reactions needed medical help.

Potential Side Effects on Lactation

A randomized research compared Naproxen and Tramadol for post -cesarean section discomfort. Patients acquired the medicines possibly on a fixed schedule or as required. No distinction in breastfeeding rates were observed among the groups.